RAF Typhoon fighter aircraft have conducted a mission with French warplanes in a coordinated attack targeting an hidden munitions depot in Syria employed by the IS group, as stated by the UK's MoD.
The location, located using reconnaissance, was believed to be storing arms and explosives, the statement said, and was positioned in hills just north of the historic site of Palmyra in central Syria.
"The RAF jets utilized Paveway IV guided bombs to hit a number of entry passages down to the facility... preliminary assessments are that the strike was effective," the MoD said.
There was no indication of any civilian casualties in the attack late on Saturday and each participating jet made a safe return, the MoD added.
The Typhoon FGR4s were supported by a Voyager aerial refuelling aircraft.
IS - alternatively referred to as ISIS - enforced extremist governance over large swathes of Syria and Iraq before its territorial defeat in 2019.
"This strike demonstrates our UK leadership, and resolve to stand shoulder to shoulder with our partners, to eliminate any resurgence of IS and their dangerous and violent ideologies in the area," the British Defence Secretary John Healey said.
British military aircraft have performed surveillance missions over Syria to "deter any attempted resurgence" of IS following its military defeat at the battle of Baghuz in 2019, the authorities noted.
"I must thank the personnel of British forces participating in this strike for their professionalism and their valour," Healey commented. "They were among a great many UK service members on duty over the holidays. This action, to eliminate dangerous terrorists who threaten our way of life, highlights how our armed forces are prepared to act, continuously, ensuring Britain's security domestically and powerful internationally."
Last December, the United States armed forces executed what it described as a "major assault" on Islamic State objectives in the country, subsequent to an attack claimed the lives of two American soldiers and a local interpreter in Palmyra.
The United Nations estimates Islamic State still has between 5,000 and 7,000 militants in Syria and Iraq.
